Trivaris Side Effects

Please note - some side effects for Trivaris may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Trivaris Side Effects - for the Professional

Trivaris

Side Effects by Body System

Cardiovascular

Cardiovascular side effects have included bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, myocardial rupture following recent myocardial infarction, pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, and vasculitis.

Dermatologic

Dermatologic side effects have included acne, allergic dermatitis, cutaneous and subcutaneous atrophy, dry scalp, edema, facial erythema, hyper or hypo-pigmentation, impaired wound healing, increased sweating, petechiae and ecchymoses, rash, sterile abscess, striae, suppressed reactions to skin tests, thin fragile skin, thinning scalp hair, and urticaria.

Endocrine

Endocrine side effects have included abnormal fat deposits, decreased carbohydrate tolerance, development of Cushingoid state, hirsutism, manifestations of latent diabetes mellitus and increased requirements for insulin or oral hypoglycemic agents in diabetics, menstrual irregularities, moon facies, and secondary adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery or illness).

Gastrointestinal

Gastrointestinal side effects have included abdominal distention, elevation in serum liver enzymes levels (usually reversible upon discontinuation), hepatomegaly, hiccups, malaise, nausea, pancreatitis, peptic ulcer with possible perforation and hemorrhage, and ulcerative esophagitis.

Hypersensitivity

Hypersensitivity side effects have included anaphylactoid reaction, anaphylaxis, and angioedema.

Metabolic

Metabolic side effects have included negative nitrogen balance due to protein catabolism and Potassium loss, hypokalemic alkalosis, and sodium retention.

Musculoskeletal

Musculoskeletal side effects have included aseptic necrosis of femoral and humeral heads, charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, steroid myopathy, tendon rupture, and vertebral compression fractures.

Nervous system

Nervous system side effects have included arachnoiditis, convulsions, depression, emotional instability, euphoria, headache, increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually following discontinuation of treatment, insomnia, meningitis, neuritis, neuropathy, paraparesis/paraplegia, paresthesia, sensory disturbances, and vertigo.

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