Trilipix Side Effects

Generic Name: fenofibric acid

Note: This page contains side effects data for the generic drug fenofibric acid. It is possible that some of the dosage forms included below may not apply to the brand name Trilipix.

It is possible that some side effects of Trilipix may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to fenofibric acid: oral capsule delayed release, oral tablet

As well as its needed effects, fenofibric acid (the active ingredient contained in Trilipix) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking fenofibric acid, check with your doctor immediately:

More common
  • Body aches or pain
  • chills
  • cough
  • difficulty with breathing
  • ear congestion
  • fever
  • headache
  • loss of voice
  • nasal congestion
  • runny nose
  • sneezing
  • sore throat
  • unusual tiredness or weakness
Less common
  • Bladder pain
  • bloody or cloudy urine
  • blurred vision
  • cough producing mucus
  • diarrhea
  • difficult, burning, or painful urination
  • difficulty with moving
  • dizziness
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aching or cramping
  • muscle or bone pain
  • muscle pain or stiffness
  • muscle spasms
  • nausea
  • nervousness
  • pain in the arms or legs
  • pounding in the ears
  • shivering
  • shortness of breath
  • slow or fast heartbeat
  • sweating
  • swollen joints
  • tightness in the chest
  • trouble sleeping
  • vomiting
  • wheezing

Some fenofibric acid side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common
  • Acid or sour stomach
  • belching
  • difficulty having a bowel movement (stool)
  • heartburn
  • indigestion
  • pain or tenderness around the eyes and cheekbones
  • sleeplessness
  • stomach discomfort, upset, or pain
  • unable to sleep

For Healthcare Professionals

Applies to fenofibric acid: oral delayed release capsule, oral tablet

Gastrointestinal

Gastrointestinal side effects of fenofibric acid (the active ingredient contained in Trilipix) alone or when co-administered with statins have included constipation (2.4% to 3.3%), diarrhea (3.1% to 6.9%), abdominal pain (4.6%), dyspepsia (2.4% to 4.7%), and nausea (3.5% to 5.5%).

Respiratory

Respiratory side effects of fenofibric acid (the active ingredient contained in Trilipix) alone or when co-administered with statins have included respiratory disorder (6.2%), rhinitis (2.3%), nasopharyngitis (3.3% to 4.7%), sinusitis (1.6% to 3.5%), and upper respiratory tract infection (2.9% to 5.3%). Respiratory side effects (greater than or equal to 3%) reported in long-term co-administration studies have included cough, pharyngolaryngeal pain, bronchitis, and influenza.

Musculoskeletal

Musculoskeletal side effects of fenofibric acid (the active ingredient contained in Trilipix) alone or when co-administered with a statin, have included pain (1.4% to 3.5%), arthralgia (3.5% to 4.9%), back pain (3.3% to 6.5%), muscle spasms (1.6% to 4.9%), myalgia (3.1% to 6.1%), and pain in extremity (2.7% to 4.5%). Musculoskeletal side effects (greater than or equal to 3%) reported in long-term co-administration studies have included musculoskeletal pain, increased blood creatine phosphokinase (CPK), and increased aspartate aminotransferase (AST).

Nervous system

Nervous system side effects of fenofibric acid (the active ingredient contained in Trilipix) alone or when co-administered with statins, have included fatigue (2.0% to 3.3%), dizziness (0.8% to 4.1%) and headache (11.9% to 16.7%). Nervous system side effects (greater than or equal to 3%) reported in long-term co-administration studies have included insomnia and hypertension.

Hepatic

Hepatic side effects of fenofibric acid (the active ingredient contained in Trilipix) alone or when co-administered with a statin have included abnormal liver tests (7.5%), increased ALT (0.4% to 3.1%), creatine phosphokinase increased (3%), and increased AST (3.4%). Hepatic side effects (greater than or equal to 3%) reported in long-term co-administration have included increased hepatic enzyme.

Genitourinary

Genitourinary side effects (greater than or equal to 3%) reported in long-term co-administration studies have included urinary tract infection.

Other

Other side effects reported postmarketing have included pancreatitis, acute renal failure, hepatitis, uremia, and cirrhosis.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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