Ojjaara Side Effects

Generic name: momelotinib

Medically reviewed by Drugs.com. Last updated on Jun 14, 2023.

Note: This document contains side effect information about momelotinib. Some dosage forms listed on this page may not apply to the brand name Ojjaara.

Applies to momelotinib: oral tablet.

Serious side effects of Ojjaara

Along with its needed effects, momelotinib (the active ingredient contained in Ojjaara) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking momelotinib:

More common

Black, tarry stools
bladder pain
bleeding gums
bloating or swelling of the face, arms, hands, lower legs, or feet
blood in the stools
bloody or cloudy urine
blurred vision
chest pain or tightness
confusion
coughing up blood
cough or hoarseness
diarrhea
difficult, burning, or painful urination
difficulty in breathing or swallowing
dizziness
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fainting
fast, slow, or irregular heartbeat
fever or chills
frequent urge to urinate
headache
increased menstrual flow or vaginal bleeding
loss of taste or smell
lower back or side pain
muscle or body aches
nausea or vomiting
nosebleeds
pale skin
paralysis
pinpoint red spots on the skin
prolonged bleeding from cuts
rapid weight gain
red or dark brown urine
sore throat
stuffy or runny nose
sweating
tingling of the hands or feet
ulcers, sores, or white spots in the mouth
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight gain or loss

Less common

Blue lips, fingernails, or skin
burning, numbness, tingling, or painful sensations
decreased urine output
dilated neck veins
nerve pain
swelling of the face, fingers, feet, or lower legs
unsteadiness or awkwardness
weakness in the arms, hands, legs, or feet

Incidence not known

Anxiety
chest discomfort
dark urine
difficulty in speaking
double vision
general feeling of illness
inability to move the arms, legs, or facial muscles
inability to speak
loss of appetite
pain, redness, or swelling in the arm or leg
pain or discomfort in the arms, jaw, back, or neck
pains in the chest, groin, or legs, especially the calves of legs
persistent non-healing sore
pink growth
reddish patch or irritated area
severe headaches of sudden onset
shiny bump
slow speech
stomach pain, severe
sudden loss of coordination
sudden onset of slurred speech
sudden vision changes
swollen glands
white, yellow or waxy scar-like area
yellow eyes or skin

Other side effects of Ojjaara

Some side effects of momelotinib may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
itching skin
pain in the arms or legs

Less common

Feeling of warmth
redness of the face, neck, arms and occasionally, upper chest

For Healthcare Professionals

Applies to momelotinib: oral tablet.

General

Serious adverse reactions occurred in up to 35% of patients and the most common of these reactions included bacterial and viral infections, hemorrhage, acute kidney injury, pneumonia, pyrexia, thrombosis, syncope, thrombocytopenia, and renal and urinary tract infection.^[Ref]

Cardiovascular

Very common (10% or more): Hemorrhage (up to 22%), hypotension (up to 14%)

Common (1% to 10%): Thrombosis, arrhythmia, heart failure

Frequency not reported: Flushing^[Ref]

Dermatologic

Very common (10% or more): Rash (up to 12%)^[Ref]

Gastrointestinal

Very common (10% or more): Diarrhea (up to 22%), nausea (up to 20%), abdominal pain (up to 18%)

Common (1% to 10%): Vomiting^[Ref]

Hematologic

Very common (10% or more): Thrombocytopenia (up to 28%)

Common (1% to 10%): Neutropenia^[Ref]

Hepatic

Very common (10% or more): Elevated liver enzymes (up to 11%)^[Ref]

Metabolic

Common (1% to 10%): Vitamin B1 deficiency^[Ref]

Musculoskeletal

Very common (10% or more): Pain in extremity (up to 12%)

Common (1% to 10%): Back pain^[Ref]

Nervous system

Very common (10% or more): Dizziness (up to 24%), headache (up to 11%)

Common (1% to 10%): Syncope, paresthesia

Frequency not reported: Neuralgia, peripheral neuropathy, peripheral motor neuropathy, polyneuropathy^[Ref]

Ocular

Frequency not reported: Blurred vision^[Ref]

Other

Very common (10% or more): Fatigue (up to 22%), bacterial infection (up to 21%), pyrexia (up to 12%), renal and urinary tract infection (up to 12%), peripheral edema (up to 11%)

Common (1% to 10%): Viral infection (excludes opportunistic infections)

Frequency not reported: Fungal infections (excludes opportunistic infections)^[Ref]