Methscopolamine / phenylephrine Side Effects

Not all side effects for methscopolamine / phenylephrine may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to methscopolamine / phenylephrine: extended-release tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth, nose, or throat; excitability or irritability (especially in children); flushing; headache; nausea; nervousness.

Seek medical attention right away if any of these SEVERE side effects occur while taking methscopolamine / phenylephrine:

Severe allergic reactions (difficulty breathing; hives; itching; rash; swelling of the mouth, tightness in the chest; face, lips, or tongue); blurred vision; clumsiness; difficulty swallowing; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; tremor; trouble sleeping; trouble urinating; unusual bleeding or bruising; vomiting.

For Healthcare Professionals

Applies to methscopolamine / phenylephrine: oral tablet extended release

Nervous system

Nervous system side effects have included drowsiness, lassitude, giddiness, increased irritability or excitement.[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea and dryness of mouth.[Ref]

Cardiovascular

Cardiovascular side effects have included palpitations and flushing.[Ref]

Ocular

Ocular side effects have included blurred vision.[Ref]

References

1. "Product Information. Extendryl PEM (methscopolamine-phenylephrine)." Auriga Laboratories Inc, Norcross, GA.

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