Jetrea Side Effects

Generic Name: ocriplasmin ophthalmic

Note: This document contains side effect information about ocriplasmin ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Jetrea.

Some side effects of Jetrea may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to ocriplasmin ophthalmic: intraocular solution

Along with its needed effects, ocriplasmin ophthalmic (the active ingredient contained in Jetrea) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking ocriplasmin ophthalmic:

More common
  • Bloody eyes
  • blurred vision or other change in vision
  • decreased vision
  • eye pain
  • redness of the eye
  • seeing flashes or sparks of light
  • sensitivity of the eye to light
  • tearing
Less common
  • Change in color vision
  • difficulty seeing at night
  • eye discomfort
  • loss of vision
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
  • throbbing pain

Some side effects of ocriplasmin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Dry eyes

For Healthcare Professionals

Applies to ocriplasmin ophthalmic: intraocular solution

General

The most frequently reported side effects (incidence of 5% to 20% in descending order of frequency) were: vitreous floaters, conjunctival hemorrhage, eye pain, photopsia, blurred vision, macular hole, reduced visual acuity, visual impairment, and retinal edema.

Immunologic

Frequency not reported: Potential for immunogenicity

Ocular

Common (1% to 10%): Macular edema, anterior chamber cell, photophobia, vitreous detachment, ocular discomfort, iritis, cataract, dry eye, metamorphopsia, conjunctival hyperemia, retinal degeneration, intraocular inflammation, decrease of less than or equal to 3 line of best corrected visual acuity (BCVA), increased intraocular pressure, intraocular hemorrhage, dyschromatopsia
Uncommon (0.1% to 1%): Retinal tear, lens detachment
Frequency not reported: Lens subluxation

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