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Japanese encephalitis virus vaccine nakayama Side Effects

For the Consumer

Applies to japanese encephalitis virus vaccine nakayama: subcutaneous powder for suspension

In addition to its needed effects, some unwanted effects may be caused by japanese encephalitis virus vaccine nakayama. In the event that any of these side effects do occur, they may require medical attention. It is very important that you tell your doctor about any side effect that occurs after a dose of the vaccine, even if the side effect goes away without treatment. Some types of side effects may mean that you should not receive any more doses of the vaccine.

Get emergency help immediately if the following side effect occurs:

  • Swelling of face, lips, eyelids, throat, tongue, hands, or feet

Severity: Major

You should check with your doctor immediately if any of these side effects occur when taking japanese encephalitis virus vaccine nakayama:

  • Hives
  • tiredness or weakness (severe or unusual)
  • wheezing or troubled breathing

Severity: Moderate

If any of the following side effects occur while taking japanese encephalitis virus vaccine nakayama, check with your doctor or nurse as soon as possible:

More common:
  • Tenderness, soreness, redness, or swelling at place of injection
Less common:
  • Abdominal pain
  • aches or pains in muscles
  • chills or fever
  • dizziness
  • general feeling of discomfort or illness
  • headache
  • itching or skin rash
  • nausea or vomiting
  • Joint swelling

For Healthcare Professionals

Applies to japanese encephalitis virus vaccine nakayama: subcutaneous powder for injection


The majority of adverse effects associated with Japanese encephalitis vaccine have been local and mild systemic effects. In some studies, less than 1% of adverse events were classified as severe. Side effects reportedly decrease with subsequent injections; however, in some cases reactions have occurred with second or third doses, after uneventful prior doses.

Any allergic and unusual adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS) at 1-800-822-7967 (USA) and to the manufacturer.[Ref]


Local side effects have included tenderness, redness, swelling in <1% up to 31% of vaccinees. Local soreness and redness reportedly decreases with subsequent injections.[Ref]


Dermatologic side effects have included rash and urticaria. Some vaccinees had generalized itching without evidence of a rash. Refractory urticaria requiring intravenous steroids has also been reported.[Ref]


Hypersensitivity or hypersensitivity-like reactions have included hives (0.2%), facial swelling (0.1%), generalized urticaria, angioedema of the extremities, and face, especially the lips and oropharynx, erythema multiforme, erythema nodosum, joint swelling, respiratory distress, hypotension, and collapse.[Ref]

Nervous system

Nervous system side effects have rarely included encephalitis, encephalopathy, seizures, peripheral neuropathy, transverse myelitis, cranial nerve paresis, cerebellar ataxia, behavior disorder, acute disseminated encephalomyelitis, and Bell's palsy.[Ref]


Cardiovascular side effects have included fatal myocarditis in a patient who received Japanese encephalitis vaccine and meningococcal vaccine, and sudden death in a patient with a history of hypersensitivity and possible anaphylaxis who also received plague vaccine. Hypotension has been reported in conjunction with allergic-like symptoms.[Ref]


Gastrointestinal side effects have included nausea, vomiting, and abdominal pain in 10% of vaccinees.[Ref]


Ocular side effects have included optic neuritis in a patient who received Japanese encephalitis vaccine concurrently with multiple other vaccines.[Ref]


Respiratory side effects have included dyspnea and wheezing in conjunction with allergic-like symptoms.[Ref]


Other systemic side effects have included fever, dizziness, flu-like symptoms, headache, myalgia, malaise, and chills in 5% to 10% of vaccinees. Headache and febrile episodes were reported in 15.2% and 5.5%, respectively.[Ref]

Serious adverse events have included Guillain-Barre syndrome in a patient who had mononucleosis; one case of urticaria, hepatitis, respiratory failure, eosinophilia, and pulmonary effusion and infiltrate; respiratory and renal failure in a patient with acid fast bacilli in sputum and pulmonary infiltrate; and hypertension of unknown etiology in a patient who developed a headache several hours after the first dose. Causality has not been determined.[Ref]


1. "Product Information. Je-Vax (Japanese encephalitis virus vaccine)." Aventis Pharmaceuticals, Swiftwater, PA.

Not all side effects for japanese encephalitis virus vaccine nakayama may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.