Inspra Side Effects
Generic Name: eplerenone
Please note - some side effects for Inspra may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
Side Effects of Inspra - for the Consumer
Inspra
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Inspra:
Seek medical attention right away if any of these SEVERE side effects occur when using Inspra:Cough; diarrhea; dizziness; flu-like symptoms (fever, chills, muscle ache, tiredness); headache; stomach pain.
TopSevere allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal vaginal discharge; chest pain; enlarged or swollen breasts; irregular heartbeat; severe muscle weakness.
Inspra Side Effects - for the Professional
Inspra
CHF Post-MI: Most common adverse reactions (>2% and more frequent than with placebo): hyperkalemia and increased creatinine. (6.1)
Hypertension: Most common adverse reactions (≥2% and more frequent than with placebo): dizziness, diarrhea, coughing, fatigue and flu-like symptoms. (6.1)
To report SUSPECTED ADVERSE REACTIONS, contact Pfizer Inc. at 1-800-438-1985 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch
Side Effects by Body System
Metabolic
Metabolic side effects have included hyperkalemia (>5.5 mEq/L). Hyperkalemia was observed in 2.6% of patients with creatinine clearance greater than 100 mL/min, in 5.6% of patients with creatinine clearance of 70 to 100 mL/min, and in 10.4% of patients with creatinine clearance less than 70 mL/min. The principal risk of eplerenone is hyperkalemia, which can result in serious, sometimes fatal arrhythmias.
Other metabolic side effects have included hypercholesterolemia and hypertriglyceridemia in 1% of patients.
Nervous system
Nervous system side effects have included dizziness (3%) and headache. In a pharmacokinetic study, headache was reported in 14% to 63% of patients.
General
General side effects have included fatigue and influenza-like symptoms.
Renal
Renal side effects have included albuminuria in 1% of patients.
Respiratory
Respiratory side effects have included cough in 2% of patients.
Gastrointestinal
Gastrointestinal side effects have included diarrhea in 2% and abdominal pain in 1% of patients.
Endocrine
Endocrine side effects have included gynecomastia (up to 1%) and mastodynia (up to 1.3%) of male patients. Abnormal vaginal bleeding was reported in 2.5% of female patients.
Hepatic
Hepatic side effects have included increases in serum alanine aminotransferase (ALT) and gamma glutamyl transpeptidase (GGT).
TopMore resources:
Inspra - Includes detailed dosage instructions.
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
A to Z Drug List
Drugs by Condition
Drug Side Effects
Natural Products
Community Forums
Interactions Checker
MedNotes
Support Groups
Drug Image Search
Phonetic Search
FDA Drug Alerts
New Drug Approvals
New Drug Applications
Clinical Trial Results
Medical Encyclopedia
News Feeds
Drugs by Classification
Patient Care Notes
Drug Imprint Codes
Medical Dictionary
Subscribe to our popular newsletter containing a regular roundup of medication news, alerts and new drug approvals.
