Increlex Side Effects

Generic Name: mecasermin

Note: This document contains side effect information about mecasermin. Some of the dosage forms listed on this page may not apply to the brand name Increlex.

Some side effects of Increlex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to mecasermin: subcutaneous solution

Along with its needed effects, mecasermin (the active ingredient contained in Increlex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mecasermin:

More common
  • Anxiety
  • bluish skin color of the fingertips
  • blurred vision
  • breathlessness
  • chest pain
  • chills
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • depression
  • dizziness
  • fast heartbeat
  • headache
  • increased hunger
  • loss of hearing
  • nausea
  • nervousness
  • nightmares
  • rapid growth of normal cells of the thymus (no symptoms)
  • seizures
  • shakiness
  • slurred speech
  • thickening of the skin
  • unusual tiredness or weakness
Incidence not known
  • Change in the ability to see colors, especially blue or yellow
  • cough
  • difficult or labored breathing
  • difficulty with swallowing
  • hives or welts
  • itching
  • itching or hives at the injection site
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • limp
  • pain in the hip or knee
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • shortness of breath
  • skin rash
  • tightness in the chest
  • vomiting
  • wheezing

Get emergency help immediately if any of the following symptoms of overdose occur while taking mecasermin:

Symptoms of overdose
  • Anxiety
  • arm or leg pain
  • backache
  • changes in vision
  • excessive sweating
  • extreme weakness
  • frequent urination
  • increase in hands and feet size
  • increased thirst
  • increased volume of pale, diluted urine
  • joint pain
  • stop in menstruation

Some side effects of mecasermin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abnormal response of the tympanic membrane to air pressure
  • difficulty with moving
  • difficulty with swallowing
  • ear pain
  • earache
  • large, flat, blue or purplish patches in the skin
  • muffled hearing
  • muscle pain or stiffness
  • redness or swelling in the ear
  • sense of fullness in the ear
  • snoring
  • sore throat
  • voice changing

For Healthcare Professionals

Applies to mecasermin: subcutaneous solution

Local

Local side effects have included lipohypertrophy and bruising.

Cardiovascular

Cardiovascular side effects have included cardiac murmur.

Gastrointestinal

Gastrointestinal side effects have included vomiting.

Hematologic

Hematologic side effects have included thymus hypertrophy.

Musculoskeletal

Musculoskeletal side effects have included arthralgia and pain in extremities. Slipped capital femoral epiphysis and progression of scoliosis has been reported.

Respiratory

Respiratory side effects have included snoring and tonsillar hypertrophy.

Metabolic

Metabolic side effects have included hypoglycemia.

Other

Other side effects have included otitis media, serous otitis media, hypoacusis, fluid in middle ear, ear pain and abnormal tympanometry.

Nervous system

Nervous system side effects have included headache, dizziness, and convulsions. Intracranial hypertension has been reported.

Hypersensitivity

Hypersensitivity side effects have included anaphylaxis, generalized urticaria, angioedema, and dyspnea.

Dermatologic

Dermatologic side effects have included postmarketing reports of alopecia and abnormal hair texture.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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