Hexalen Side Effects

Generic name: altretamine

Medically reviewed by Drugs.com. Last updated on Oct 26, 2023.

Note: This document contains side effect information about altretamine. Some dosage forms listed on this page may not apply to the brand name Hexalen.

Applies to altretamine: oral capsule.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using altretamine (the active ingredient contained in Hexalen) and call your doctor at once if you have:

• severe numbness, tingling, or cold feeling in your hands or feet;

• severe or continuous vomiting;

• fever, chills, flu symptoms, mouth sores, pale skin, easy bruising or bleeding, unusual weakness;

• a light-headed feeling, like you might pass out;

• severe dizziness or spinning sensation;

• seizure (convulsions); or

• upper stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

• mild nausea or vomiting;

• mild numbness or tingling;

• loss of appetite;

• mood changes, mild dizziness; or

• skin rash, itching, hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to altretamine: oral capsule.

Hematologic

Very common (10% or more): Anemia (33%)

Common (1% to 10%): Thrombocytopenia, leukopenia^[Ref]

Gastrointestinal

Very common (10% or more): Nausea and vomiting (33%)

Common (1% to 10%): Increased alkaline phosphatase^[Ref]

Nervous system

Very common (10% or more): Peripheral sensory neuropathy (31%)

Common (1% to 10%): Seizures

Frequency not reported: CNS symptoms (mood disorders, disorders of consciousness, ataxia, dizziness, vertigo)^[Ref]

Renal

Common (1% to 10%): Increased BUN, increased serum creatinine^[Ref]

Metabolic

Uncommon (0.1% to 1%): Anorexia^[Ref]

Other

Uncommon (0.1% to 1%): Fatigue^[Ref]

Hepatic

Frequency not reported: Hepatic toxicity^[Ref]

Dermatologic

Frequency not reported: Skin rash, pruritus, alopecia^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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