Galzin Side Effects

Please note - some side effects for Galzin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Galzin - for the Consumer

Galzin

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Galzin:

Nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe vomiting; unusual restlessness; very dry mouth, eyes, or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Galzin Side Effects - for the Professional

Galzin

Clinical experience with zinc acetate has been limited. The following adverse reactions have been reported in patients with Wilson’s disease on zinc therapy: a death following overdosage with zinc sulfate and a death in a patient with advanced liver disease and hemolytic crisis where zinc sulfate was used as initial treatment; gastric irritation; elevations of serum alkaline phosphatase, amylase and lipase lasting from weeks to months suggesting pancreatitis. The levels usually return to high normal within the first one or two years of zinc therapy.

Drug Abuse and Dependence

Zinc acetate has no potential for abuse, and it is not related pharmacologically or structurally to any other drug known to have abuse potential.

Side Effects by Body System - for Healthcare Professionals

General

In general, zinc acetate is relatively nontoxic if used at recommended dosages.

Hepatic

Although elevations in amylase, lipase and alkaline phosphatase have not been associated with any clinically significant events during clinical trials, it is suggested that liver and pancreatic function be closely monitored during zinc acetate therapy.

Hypocalcemia and decreased bone resorption have been demonstrated in animal models receiving high levels of dietary zinc.

Hepatic side effects have included increases in amylase and lipase.

Endocrine

Endocrine side effects have included the reduction of high density lipoprotein (HDL) in males.

Due to an accompanying decrease in low density lipoproteins (LDL), the LDL/HDL ratio remains relatively unchanged and little risk is assumed in terms of coronary heart disease. Triglyceride levels have not been shown to be affected.

Immunologic

In healthy subjects receiving zinc as a dietary supplement, lymphocyte stimulation, polymorphonuclear migration and phagocytosis were impaired. The clinical significance of this effect is unknown.

Immunologic side effects have included a decrease in the immunologic response.

Hematologic

Hematologic side effects have NOT included hematologic abnormalities due to iron deficiency anemia.

Because zinc competes with the absorption of iron, copper and other minerals, it may be necessary to monitor the patient's iron status for any possible deficiencies.

Gastrointestinal

Gastrointestinal side effects have been reported the most frequently. These have included gastrointestinal upset, which may occur in up to 10% of patients.

Gastrointestinal irritation appears to be dose-related.

To alleviated gastric upset and increase compliance, it has been suggested to administer the first morning dose between breakfast and lunch, rather than before breakfast.

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