Follistim AQ Side Effects
Generic Name: follicle stimulating hormone
Note: This document contains side effect information about follicle stimulating hormone. Some of the dosage forms listed on this page may not apply to the brand name Follistim AQ.
Some side effects of Follistim AQ may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to follicle stimulating hormone: subcutaneous kit, subcutaneous powder for solution, subcutaneous solution
Other dosage forms:
Along with its needed effects, follicle stimulating hormone (the active ingredient contained in Follistim AQ) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking follicle stimulating hormone:More common
- Abdominal or stomach pain that is severe
- severe nausea or vomiting
- stomach or pelvic discomfort, aching, or heaviness
- weight gain that is rapid
- Heavy non-menstrual vaginal bleeding
- redness, pain, or swelling at the injection site
- unusual tiredness or weakness
- Difficulty with breathing
- pain in the chest, groin, or legs, especially the calves
- severe, sudden headache
- slurred speech
- sudden loss of coordination
- sudden, severe weakness or numbness in the arm or leg
- sudden, unexplained shortness of breath
- vision changes
Some side effects of follicle stimulating hormone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Blemishes on the skin
- Body aches or pain
- difficulty having a bowel movement (stool)
- dry skin
- fast or racing heart
- hair loss
- quick or shallow breathing
- swelling of the breasts or breast soreness in both females and males
- Breast tenderness
- normal menstrual bleeding occurring earlier, possibly lasting longer than expected
For Healthcare Professionals
Applies to follicle stimulating hormone: injectable powder for injection, injectable solution, subcutaneous powder for injection, subcutaneous solution
Mild to moderate uncomplicated ovarian enlargement has been reported to generally regress without treatment within two or three weeks.
Severe OHSS may progress over one to several days to become a serious medical event. Severe OHSS is characterized by an apparent dramatic increase in vascular permeability which can result in a rapid accumulation of fluid in the peritoneal cavity, thorax, and potentially the pericardium. Early warning signs include severe pelvic pain, nausea, vomiting, and weight gain. Cases of OHSS may include abdominal pain, abdominal distension, nausea, vomiting, diarrhea, severe ovarian enlargement, weight gain, dyspnea, and oliguria. Clinical evaluation may reveal hypovolemia, hemoconcentration, electrolyte imbalances, ascites, hemoperitoneum, pleural effusions, hydrothorax, acute pulmonary distress, and thromboembolic events. Transient liver function test abnormalities have also been associated with OHSS.
Genitourinary side effects have included mild to moderate ovarian enlargement sometimes accompanied by abdominal distention and/or abdominal pain, severe ovarian hyperstimulation syndrome (OHSS), miscarriage, ectopic pregnancy and ovarian cysts. Other genitourinary side effects have included intermenstrual bleeding, dysmenorrhea, breast tenderness, urinary tract infection, vaginal hemorrhage and moniliasis genital.
Other respiratory tract side effects have included sinusitis, pharyngitis, coughing, rhinitis, dyspnea, tachypnea and upper respiratory tract infection.
Respiratory effects have included atelectasis, pulmonary embolism, pulmonary infarction, and acute respiratory distress syndrome. In rare cases, pulmonary complications have resulted in death.
Cardiovascular effects have included venous thrombophlebitis, cerebral vascular occlusion (stroke), and arterial occlusion resulting in loss of limb. In rare cases, thromboembolic events have resulted in death.
Other cardiovascular side effects have included chest pain, palpitations, and tachycardia.
Other side effects have included febrile reactions and flu-like symptoms which included fever, chills, musculoskeletal aches, joint pains, malaise, headache, and fatigue.
It is not clear whether the febrile reactions were pyrogenic responses or possible allergic reactions.
Gastrointestinal effects have included anorexia, nausea, vomiting, diarrhea, abdominal pain, flatulence, and dyspepsia.
Local side effects have included pain, rash, swelling, and/or irritation at the site of injection.
Dermatologic side effects have included dry skin, body rash, hair loss, acne, pruritus and hives.
Psychiatric side effects have included emotional liability.
Metabolic side effects have included weight gain.
Nervous system side effects have included headache, paresthesias somnolence, anxiety and dizziness.
Musculoskeletal side effects have included myalgia, back pain and joint pains.
More about Follistim AQ (follicle stimulating hormone)
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