Cloderm Side Effects

Generic Name: clocortolone topical

Note: This page contains information about the side effects of clocortolone topical. Some of the dosage forms included on this document may not apply to the brand name Cloderm.

Not all side effects for Cloderm may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to clocortolone topical: topical cream

Get emergency medical help if you have any of these signs of an allergic reaction while taking clocortolone topical (the active ingredient contained in Cloderm) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing clocortolone topical through your skin, such as:

  • blurred vision, or seeing halos around lights;

  • mood changes;

  • sleep problems (insomnia);

  • weight gain, puffiness in your face; or

  • muscle weakness, feeling tired.

Less serious side effects of clocortolone topical may include:

  • mild skin itching, burning, peeling, or dryness;

  • thinning or softening of your skin;

  • skin rash or irritation around your mouth;

  • swollen hair follicles;

  • changes in color of treated skin;

  • blisters, pimples, or crusting of treated skin; or

  • stretch marks.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

For Healthcare Professionals

Applies to clocortolone topical: topical cream

Endocrine

Endocrinologic side effects have included the suppression of the hypothalamic-pituitary-adrenal axis. This suppression is more likely when higher potency topical steroids are used over extensive areas and when occlusive dressings are used.

General

Clocortolone topical (the active ingredient contained in Cloderm) has been generally well tolerated.

Local

Local side effects have commonly included burning, itching, or irritation, especially when applied to denuded skin or with occlusive dressings. Long-term use of topical corticosteroids may result in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis is occasionally reported.

Skin on the face, axillae, and groin appear to be most susceptible to the adverse, long-term effects of topical steroids.

Topical corticosteroid use may inhibit local immune response rendering the skin more susceptible to infections. Folliculitis has occasionally been reported.

Perioral dermatitis or rosacea-like dermatitis has occurred in patients treated with potent topical corticosteroids who are of seborrheic skin type. This condition may flare temporarily upon discontinuation of topical steroids, prompting patients to continue their use. If topical corticosteroids are discontinued, this flare and the initial dermatitis generally resolves over a few weeks.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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