Bisacodyl / polyethylene glycol 3350 / potassium chloride / sodium bicarbonate / sodium chloride Side Effects
Not all side effects for bisacodyl / polyethylene glycol 3350 / potassium chloride / sodium bicarbonate / sodium chloride may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to bisacodyl / polyethylene glycol 3350 / potassium chloride / sodium bicarbonate / sodium chloride: solution, tablet
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking bisacodyl / polyethylene glycol 3350 / potassium chloride / sodium bicarbonate / sodium chloride:
Discomfort; feeling of being full or bloated; mild stomach pain, cramping, or discomfort; nausea.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); decreased urination; fainting; irregular heartbeat; rectal bleeding; seizures; severe or persistent nausea; severe or persistent stomach pain, bloating, cramping, or discomfort; symptoms of dehydration (eg, very dry mouth or eyes, increased thirst, fast heartbeat, dizziness, headache, sluggishness); vomiting.
For Healthcare Professionals
Applies to bisacodyl / polyethylene glycol 3350 / potassium chloride / sodium bicarbonate / sodium chloride: oral kit
Mallory-Weiss tears are quite rare with administration of PEG-ELS. In one study it occurred in only 0.06% of over 3,000 patients.
Complete rectal prolapse was reported in a 71-year-old who had been given 4 L of PEG-ELS. The patient was observed for 2 days and had no recurrence of the prolapse.
During administration of PEG-ELS (4 liters) two deaths occurred in patients with end-stage renal failure following the development of vomiting, diarrhea and dysnatremia.
Gastrointestinal side effects have been reported the most frequently. These have included nausea (17.1%), cramping (9.1%), abdominal fullness (22.3%), vomiting (5.9%) and overall discomfort (19.1%).
A small percentage of patients who received PEG-ELS have reportedly experienced Mallory-Weiss tears of the esophagus and esophageal perforation. In addition, at least one case of rectal prolapse has been reported.
Dermatologic side effects reported with PEG-ELS have rarely included urticaria and dermatitis.
Cardiovascular side effects of PEG-ELS have included arrhythmias and asystole.
Cardiac arrhythmias, especially increased ventricular ectopy, have been associated with PEG-ELS use.
The manufacturer notes an isolated case of asystole following ingestion of PEG-ELS in a geriatric patient (equal to or greater than 60 years of age).
A 70-year-old male developed shortness of breath, wheezing, skin flushing, and lowered blood pressure after drinking a second glass of PEG-ELS.
Hypersensitivity side effects with PEG-ELS have rarely included anaphylaxis.
Other side effects with PEG-ELS have included rhinorrhea.
Respiratory side effects with PEG-ELS have included sudden dyspnea with pulmonary edema, and 'butterfly-like' infiltrate on chest X-ray.
The manufacturer notes isolated reports of 'butterfly-like' infiltrate on chest X-ray following vomiting and aspiration of PEG-ELS and sudden dyspnea with pulmonary edema in geriatric patients (equal to or greater than 60-years-old).
Tonic-clonic seizures have been reported in patients with and without previous history of seizures following administration of PEG-ELS (4 liters).
Nervous system side effects have included tonic-clonic seizures.
More about bisacodyl/polyethylene glycol 3350/potassium chloride/sodium bicarbonate/sodium chloride
- Polyethylene glycol/electrolytes solution
- Bisacodyl and polyethylene glycol (PEG) 3350 with electrolytes
- Other brands: HalfLytely and Bisacodyl
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