Axert Side Effects
Generic name: almotriptan
Note: This document contains side effect information about almotriptan. Some of the dosage forms listed on this page may not apply to the brand name Axert.
Some side effects of Axert may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to almotriptan: oral tablet
Along with its needed effects, almotriptan (the active ingredient contained in Axert) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking almotriptan:Less common
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- chest pain
- discharge from the eye
- eye irritation
- fast, irregular, pounding, or racing heartbeat or pulse
- itching, redness, or swelling of the skin
- neck pain or rigid neck
- redness of inner lining of the eyelid
- skin rash
- shortness of breath
- tightness in the throat
- Abdominal or stomach cramping or pain
- black, tarry stools
- blood in the stools
- bringing back up of food
- chest pain, severe
- cool, pale skin
- difficulty with swallowing
- heartburn, repeated
- increased sweating
- loss of appetite
- loss of vision
- rapid breathing
- tightness in the chest
- weight loss
Some side effects of almotriptan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Burning, numbness, prickly, or tingling feeling
- dry mouth
- Aching, fullness, or tension in the sinuses
- anxious feeling
- back pain
- change in sense of taste
- cough producing mucus
- decreased sensitivity to touch
- feeling of constant movement of self or surroundings
- feeling of spinning
- feeling of warmth or heat
- flushing or redness of the skin
- increased sense of hearing
- lack or loss of strength
- muscle aches
- muscle weakness
- painful menstrual period
- quivering or trembling
- runny or stuffy nose
- sore throat
- trouble with sleeping
- Abnormal increase in reflexes
- abnormally increased feeling of mental and physical well-being
- buzzing or ringing in the ears
- change in dreams or nightmares
- change in sense of smell
- change in sense of touch
- clumsiness or unsteadiness
- continuous, uncontrolled, back-and-forth or rolling eye movements
- difficulty in concentrating
- double vision
- dry eyes
- dry throat
- feeling of pins and needles
- increased sensitivity to sunlight
- increased thirst
- loss of voice
- mental depression
- muscle stiffness
- pain, redness, swelling, or warmth in the joints
- stabbing pain
For Healthcare Professionals
Applies to almotriptan: oral tablet
In one study (n=20), significant effects were reported for the maximal change in diastolic blood pressure and for the maximal and mean change in systolic blood pressure.
Cardiovascular side effects, some fatal, have occurred following the use of 5-HT1 agonists. These events are extremely rare and most have been reported in patients with risk factors predictive of CAD. Such effects include coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular tachycardia, and ventricular fibrillation. Less frequently reported cardiovascular side effects have included vasodilation, palpitations, and tachycardia. Hypertension and syncope have been rarely reported.
General side effects have included headache, abdominal pain or cramp, asthenia, chills, back pain, chest pain, neck pain, fatigue, and rigid neck. Fever and photosensitivity reaction have been rarely reported. Sensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw have been reported after treatment with almotriptan (the active ingredient contained in Axert) (These events were not associated with arrhythmias or ischemic ECG changes in clinical trials.)
Gastrointestinal side effects including nausea and dry mouth have been frequently reported. Less frequently reported gastrointestinal side effects have included diarrhea, vomiting, and dyspepsia. Colitis, gastritis, gastroenteritis, esophageal reflux, increased thirst, and increased salivation have been rarely reported.
Metabolic side effects reported infrequently have included hyperglycemia and increased serum creatine phosphokinase. Increased gamma glutamyltransferase and hypercholesterolemia have been rarely reported.
Musculoskeletal side effects have included myalgia and muscular weakness. Arthralgia, arthritis, and myopathy have been rarely reported.
Nervous system side effects frequently reported have included paraesthesia, dizziness, and somnolence. Less frequently reported nervous system side effects have included tremor, vertigo, anxiety, hyperesthesia, restlessness, CNS stimulation, insomnia, and shakiness. Altered dreams, impaired concentration, abnormal coordination, depressive symptoms, euphoria, hyperreflexia, hypertonia, nervousness, neuropathy, nightmares, and nystagmus have been rarely reported.
Respiratory side effects including pharyngitis, rhinitis, dyspnea, laryngismus, sinusitis, bronchitis, and epistaxis have been reported infrequently. Hyperventilation, laryngitis, and sneezing have been reported rarely.
Dermatologic side effects including diaphoresis, dermatitis, erythema, pruritus, and rash have been infrequently reported.
Special sense reactions have included ear pain, conjunctivitis, eye irritation, hyperacusis, and taste alteration. Diplopia, dry eyes, eye pain, otitis media, parosmia, scotoma, and tinnitus have been rarely reported.
Genitourinary side effects reported infrequently have included dysmenorrhea.
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