Antipyrine / Benzocaine Otic Side Effects

Medically reviewed by Drugs.com. Last updated on Jan 4, 2024.

Applies to antipyrine/benzocaine otic: otic solution.

Important warnings This medicine can cause some serious health issues

Medicinal use of this product to treat ear infections has not been approved by the FDA.

You should not use this medicine if you have a hole in your ear drum (ruptured ear drum).

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call you doctor at once if you have:

• severe irritation after using the ear drops; or

• ear discomfort you did not have before using this medicine.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to antipyrine/benzocaine otic: otic solution.

Cardiovascular

• Frequency not reported: Blue lips, blue nail beds, change in heart rate, grey lips, grey nail beds, irregular heartbeat, pale lips, pale nail beds, pale skin, swelling^[Ref]

Dermatologic

• Frequency not reported: Blue-colored skin, grey-colored skin, itching, rash, redness^[Ref]

Nervous system

• Frequency not reported: Burning, dizziness, headache, lightheadedness^[Ref]

Gastrointestinal

• Frequency not reported: Nausea, swallowing difficulty, swollen mouth, swollen tongue^[Ref]

Other

• Frequency not reported: Fatigue, malaise, pain^[Ref]

Hematologic

• Frequency not reported: Methemoglobinemia^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity^[Ref]

Psychiatric

• Frequency not reported: Confusion^[Ref]

Musculoskeletal

• Frequency not reported: Body twitching^[Ref]

Local

• Frequency not reported: Administration site irritation^[Ref]

Respiratory

• Frequency not reported: Breathing difficulty, shortness of breath^[Ref]

Further information

Antipyrine/benzocaine otic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer