Medication Guide App

Altabax Side Effects

Generic Name: retapamulin topical

Note: This document contains side effect information about retapamulin topical. Some of the dosage forms listed on this page may not apply to the brand name Altabax.

Some side effects of Altabax may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to retapamulin topical: topical application ointment

Along with its needed effects, retapamulin topical (the active ingredient contained in Altabax) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking retapamulin topical:

Less common
  • Burning, itching, redness, skin rash, swelling, or soreness at site
  • skin rash, encrusted, scaly, and oozing
  • Blistering, burning, crusting, dryness, flaking of skin
  • flushing, redness of skin
  • itching, scaling, severe redness, soreness, swelling of skin
  • pain at site of application
  • unusually warm skin

Some side effects of retapamulin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Diarrhea
  • fever
  • headache
  • muscle aches
  • nausea
  • sore throat
  • stuffy or runny nose
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to retapamulin topical: topical ointment


Dermatologic side effects have included application site irritation (1.6%), pruritus (1.9%), and eczema (1%). Dermatologic side effects that have been reported in less than 1% of patients include application site pain, erythema, and contact dermatitis.


Other side effects have included headache (1% to 2%) and pyrexia (1.2%).


Gastrointestinal side effects have included diarrhea (1.7%) and nausea (1.2%).


Respiratory side effects have included nasopharyngitis (1.5%).

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