Alrex Side Effects
Generic Name: loteprednol ophthalmic
Note: This page contains information about the side effects of loteprednol ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Alrex.
For the Consumer
Applies to loteprednol ophthalmic: ophthalmic gel/jelly, ophthalmic ointment, ophthalmic suspension
In addition to its needed effects, some unwanted effects may be caused by loteprednol ophthalmic (the active ingredient contained in Alrex). In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking loteprednol ophthalmic:More common
- Blurred vision or other change in vision
- redness or swelling of the eye
- sensitivity of the eyes to light
- swelling of the membrane covering the white part of the eye
- Discharge from the eye
- eye discomfort, irritation, or pain
- redness of the eyelid or inner lining of the eyelid
- tiny bumps on the inner lining of the eyelid
- delayed wound healing
- loss of vision
- nausea or vomiting
Some of the side effects that can occur with loteprednol ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common
- Burning when medicine is applied
- dry eyes
- feeling of something in the eye
- runny nose
- sore throat
- tearing or watery eye
For Healthcare Professionals
Applies to loteprednol ophthalmic: ophthalmic gel, ophthalmic ointment, ophthalmic suspension
Very common (10% or more): Anterior chamber inflammation with ointment (25%), occurring in 5 to 15% of patients: Abnormal vision/blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, photophobia
Common (1% to 10%): Anterior chamber inflammation with gel (5%), conjunctival hyperemia, corneal edema, eye pain, foreign body sensation, occurring in less than 5% of patients: conjunctivitis, corneal abnormalities, eyelid erythema, keratoconjunctivitis, ocular irritation/discomfort, papillae, uveitis
Frequency not reported: Elevated intraocular pressure (may be associated with infrequent optic nerve damage), visual acuity and field defects, posterior subcapsular cataract formation, delayed wound healing, secondary ocular infection (including herpes simplex), perforation of the globe (where there is thinning of the cornea or sclera), keratitis, corneal ulcers, loss of accommodation, ptosis[Ref]
Randomized studies involving patients treated with loteprednol etabonate therapy for 28 days or longer revealed the incidence of significant elevation in intraocular pressure (>= 10 mmHg) was 2% (15/901) with loteprednol etabonate, 7% (11/164) with 1% prednisolone acetate and 0.5% (3/583) with placebo.[Ref]
Very common (10% or more): Occurring in less than 15% of patients: rhinitis, pharyngitis[Ref]
Very common (10% or more): Headache[Ref]
1. "Product Information. Alrex (loteprednol ophthalmic)." Bausch and Lomb, Tampa, FL.
2. "Product Information. Lotemax (loteprednol ophthalmic)." Bausch and Lomb, Tampa, FL.
3. "Product Information. Zylet (loteprednol-tobramycin ophthalmic)." Bausch and Lomb, Rochester, NY.
Not all side effects for Alrex may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Alrex (loteprednol ophthalmic)
- Other brands: Lotemax
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