Pentobarbital Pregnancy and Breastfeeding Warnings
Pentobarbital is also known as: Nembutal, Nembutal Sodium
Pentobarbital Pregnancy Warnings
Pentobarbital has been assigned to pregnancy category D by the FDA. An increased risk of congenital malformations has been associated with use of other barbiturates (including phenobarbital) and anticonvulsants during pregnancy. Pentobarbital has not been specifically implicated, but may pose similar risks. Defects associated with anticonvulsant use in pregnancy include neural tube defects, cleft lips, cleft palates, cardiac defects, and microcephaly. Neonatal barbiturate withdrawal symptoms have also been reported in infants whose mothers took barbiturates during pregnancy. There are no controlled data in human pregnancy. Pentobarbital should only be given during pregnancy when there are no alternatives and benefit outweighs risk.
Pentobarbital Breastfeeding Warnings
Pentobarbital is excreted into human milk in small amounts. The possibility of accumulation of other barbiturates in nursing infants has been reported, although pentobarbital has not been specifically implicated. The American Academy of Pediatrics has no formal position on pentobarbital but classifies phenobarbital as a drug which has "caused significant effects on some nursing infants and should be given to nursing mothers with caution."
See Also...
- Pentobarbital use while Breastfeeding (in more detail)
- pentobarbital Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
