Pentobarbital use while Breastfeeding

Drugs containing Pentobarbital: Nembutal, E-Caff P-B, ErgocaffPB, Migracet-PB, Nembutal Sodium, Ergocaf-PB, Cafatine PB, Micomp-PB, Ergocomp-PB, Belcomp-PB

Pentobarbital Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because there is little published experience with pentobarbital during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. A mother who was 4 days postpartum had taken pentobarbital 100 mg daily for 3 days. A milk level of 170 mcg/L was measured 19 hours after the previous dose.[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Zaleplon, Zolpidem

References

1. Horning MG, Stillwell WG, Nowlin J et al. Identification and quantification of drugs and drug metabolites in human breast milk using GC-MS-COM methods. Mod Probl Paediatr. 1975;15:73-9.

Pentobarbital Identification

Substance Name

Pentobarbital

CAS Registry Number

76-74-4

Drug Class

Administrative Information

LactMed Record Number

503

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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