Pentobarbital Levels and Effects while Breastfeeding
Summary of Use during Lactation
Because there is little published experience with pentobarbital during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant. If pentobarbital is used, monitor the infant for sedation, poor feeding and poor weight gain.
Drug Levels
Maternal Levels. A mother who was 4 days postpartum had taken pentobarbital 100 mg daily for 3 days. A milk level of 170 mcg/L was measured 19 hours after the previous dose.[1]
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Horning MG, Stillwell WG, Nowlin J, et al. Identification and quantification of drugs and drug metabolites in human breast milk using GC-MS-COM methods. Mod Probl Paediatr. 1975;15:73–9.
Substance Identification
Substance Name
Pentobarbital
CAS Registry Number
76-74-4
Drug Class
Breast Feeding
Lactation
Milk, Human
Barbiturates
Hypnotics and Sedatives
GABA Modulators
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
