Lomustine Pregnancy and Breast Feeding Warnings

Lomustine is also known as: CeeNU

Overview

Lomustine (CCNU) has been shown to cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lomustine (CCNU) while you are pregnant. It is not known if Lomustine (CCNU) is found in breast milk. Do not breast-feed while taking Lomustine (CCNU) .

Lomustine Pregnancy Warnings

Lomustine has been assigned to pregnancy category D by the FDA. Animal studies have revealed evidence of embryotoxicity and teratogenicity in rats and embryotoxicity in rabbits at dosage levels equivalent to human dosages. There are no controlled data in human pregnancy. If this drug is used during pregnancy, or if the patient becomes pregnant while receiving this drug, the patient should be apprised of the potential hazard to the fetus. Women of childbearing potential should be advised to avoid becoming pregnant during therapy. Lomustine should only be given during pregnancy when there are no alternatives and benefit outweighs risk.

Lomustine Lactation Warnings

Metabolites of lomustine have been detected in milk, but at lower concentrations than in maternal plasma. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

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