Ibuprofen Pregnancy and Breastfeeding Warnings
Ibuprofen is also known as: Addaprin, Advil, Advil Children's, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Haltran, IBU, IBU-200, Ibu-Tab, Ibuprofen PMR, Menadol, Midol IB, Motrin, Motrin Childrens, Motrin IB, Motrin Migraine Pain, Nuprin, Proprinal, Rufen, Saleto-200
Ibuprofen Pregnancy Warnings
Ibuprofen has been assigned by the FDA to pregnancy category C prior to 30 weeks gestation and pregnancy category D at greater than or equal to 30 weeks gestation. Animal studies have failed to reveal evidence of developmental abnormalities. There are no controlled data in human pregnancy. While there are no literature reports linking the use of ibuprofen in pregnancy with birth defects, use of ibuprofen at greater than or equal to 30 weeks gestation may cause premature closure of the ductus arteriosus and prolong labor and delivery. Ibuprofen should only be given during pregnancy when benefit outweighs risk and should be avoided on or after 30 weeks gestation.
In rat studies with NSAIDs, as with other drugs known to inhibit prostaglandin synthesis, an increased incidence of dystocia, delayed parturition, and decreased pup survival occurred. The effects of ibuprofen on labor and delivery in pregnant women are unknown.
Ibuprofen Breastfeeding Warnings
There are no data on the excretion of ibuprofen into human milk. The effects in the nursing infant are unknown. The manufacturer recommends that a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.