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Ibuprofen Pregnancy and Breastfeeding Warnings

Ibuprofen is also known as: Addaprin, Advil, Advil Children's, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Haltran, IBU, IBU-200, Ibu-Tab, Menadol, Midol IB, Motrin, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Migraine Pain, NeoProfen, Nuprin, Proprinal, Rufen

Ibuprofen Pregnancy Warnings

Ibuprofen has been assigned by the FDA to pregnancy category C prior to 30 weeks gestation and pregnancy category D at greater than or equal to 30 weeks gestation. Animal studies have failed to reveal evidence of developmental abnormalities. There are no controlled data in human pregnancy. While there are no literature reports linking the use of ibuprofen in pregnancy with birth defects, use of ibuprofen at greater than or equal to 30 weeks gestation may cause premature closure of the ductus arteriosus and prolong labor and delivery. Ibuprofen should only be given during pregnancy when benefit outweighs risk and should be avoided on or after 30 weeks gestation.

In rat studies with NSAIDs, as with other drugs known to inhibit prostaglandin synthesis, an increased incidence of dystocia, delayed parturition, and decreased pup survival occurred. The effects of ibuprofen on labor and delivery in pregnant women are unknown.

Ibuprofen Breastfeeding Warnings

There are no data on the excretion of ibuprofen into human milk. The effects in the nursing infant are unknown. The manufacturer recommends that a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

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