Hydromorphone Pregnancy and Breastfeeding Warnings
Hydromorphone is also known as: Dilaudid, Dilaudid-HP, Exalgo, Hydromorph Contin, Hydrostat IR, Palladone
Hydromorphone Pregnancy Warnings
Infants born to mothers physically dependent on hydromorphone will also be physically dependent and may exhibit respiratory difficulties and withdrawal symptoms.
Hydromorphone has been assigned to pregnancy category C by the FDA. Detailed information about the use of hydromorphone in pregnancy is not available. Animal studies have reported the occurrence of teratogenic effects at doses 600 times the human dose. Withdrawal symptoms have been reported in neonates whose mothers took other narcotic analgesics during pregnancy. In general, hydromorphone should only be given during pregnancy when benefit outweighs risk. However, the manufacturer reports that use of hydromorphone is contraindicated for obstetric analgesia.
Hydromorphone Breastfeeding Warnings
One study on eight lactating healthy women has reported that hydromorphone distributes rapidly from plasma into breast milk. However, the drug does not partition into fat. The suckling infant would receive approximately 0.67% of the maternal dose of hydromorphone (adjusted for body weight).
See Also...
- Hydromorphone use while Breastfeeding (in more detail)
- hydromorphone Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
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