Hydrochlorothiazide / metoprolol Pregnancy and Breastfeeding Warnings
Brand names: Dutoprol, Lopressor HCT
Medically reviewed by Drugs.com. Last updated on Jun 12, 2024.
Hydrochlorothiazide / metoprolol Pregnancy Warnings
This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.
US FDA pregnancy category: C
Animal studies have revealed evidence of decreased postnatal survival and increased postimplantation and fetal loss. There are no controlled data in human pregnancy.
US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Hydrochlorothiazide / metoprolol Breastfeeding Warnings
A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
Excreted into human milk: Yes (hydrochlorothiazide, metoprolol [in small amounts])
A mother taking metoprolol would transfer less than 1 mg/L to a breastfeeding infant.
See also
References for pregnancy information
- (2022) "Product Information. Lopressor HCT (hydrochlorothiazide-metoprolol)." Novartis Pharmaceuticals
References for breastfeeding information
- (2022) "Product Information. Lopressor HCT (hydrochlorothiazide-metoprolol)." Novartis Pharmaceuticals
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.