Guaifenesin / hydrocodone Pregnancy and Breastfeeding Warnings
Guaifenesin / hydrocodone is also known as: Co-Tussin, CodiCLEAR DH, Codotuss, Condasin, EndaCof-Tab, Entuss, Execlear, Hycosin Expectorant, Hycotuss Expectorant, Hydrocod-GF, Hydrotuss, Kwelcof, Maxi-Tuss HCG, Monte-G HC, Narcof, Obredon, Pneumotussin, Pneumotussin 2.5, Pneumotussin HC, Propatuss Expectorant, Tusso-HC, Vi-Q-Tuss, Vicodin Tuss, Vortex, Ztuss ZT
Guaifenesin / hydrocodone Pregnancy Warnings
Guaifenesin-hydrocodone has been assigned to pregnancy category C by the FDA. Animal reproduction studies have not been conducted on this combination product. There are no controlled data on this combination product in human pregnancy. Guaifenesin-hydrocodone is only recommended for use during pregnancy when benefit outweighs risk.
Detailed information about the use of hydrocodone in pregnancy is not available. Animal studies have reported the occurrence of teratogenic effects at doses 700 times the human dose. Withdrawal symptoms and respiratory depression have been reported in neonates whose mothers took other narcotic analgesics during pregnancy.
Guaifenesin / hydrocodone Breastfeeding Warnings
There are no data on the excretion of guaifenesin and hydrocodone into human milk. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue guaifenesin and hydrocodone, taking into account the importance of guaifenesin and hydrocodone to the mother.
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