Econazole topical Pregnancy and Breastfeeding Warnings
Econazole topical is also known as: Spectazole, Spectazole Cream
Econazole topical Pregnancy Warnings
Econazole vaginal cream (not available in the US) has been used for the treatment of vaginal candidiasis in pregnant patients. In one study of 117 pregnant women with a duration of pregnancy ranging form 10 to 42 weeks, patients were treated with 150 mg once a day for three days. Three stillbirths were recorded. No congenital abnormalities were recorded among any of the infants. In another study, 112 pregnant women were treated with econazole 150 mg vaginal suppositories. No malformations were observed in 99 infants for whom information following delivery was available.
Econazole topical has been assigned to pregnancy category C by the FDA. Animal studies have revealed fetotoxic and embryotoxic effects at 10 to 80 times the human dose. Econazole has been used in clinical trials for the treatment of vaginal candidiasis, generally during the second and third trimester, without evidence of fetal harm. Econazole should only be used during pregnancy when need has been clearly established.
Econazole topical Breastfeeding Warnings
There are no data on the excretion of econazole into human milk. Oral econazole is excreted into rat milk. The manufacturer recommends that caution be used when administering econazole topical to nursing women.
- Econazole use while Breastfeeding (in more detail)
- econazole cream Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.