Didanosine Pregnancy and Breastfeeding Warnings
Didanosine Pregnancy Warnings
An Antiretroviral Pregnancy Registry has been established to monitor maternal-fetal outcomes of didanosine exposures during pregnancy. To register patients, physicians should call 800-258-4263. Fatal lactic acidosis has been reported in pregnant women who received the combination of didanosine and stavudine with other antiretroviral agents. The combination of didanosine and stavudine should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk.
Didanosine has been assigned to pregnancy category B by the FDA. Animal studies failed to reveal harm to the fetus. There are no controlled data in human pregnancies. Didanosine should only be given during pregnancy when need has been clearly established.
Didanosine Breastfeeding Warnings
There are no data on the excretion of didanosine into human milk. It is excreted into rat milk. The U.S. Public Health Service Centers for Disease Control and Prevention advise HIV-infected women not to breast-feed to avoid postnatal transmission of HIV to a child who may not yet be infected.
- Didanosine use while Breastfeeding (in more detail)
- didanosine chewable/dispersible buffered tablets Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
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