Diclofenac ophthalmic Pregnancy and Breastfeeding Warnings
Diclofenac ophthalmic is also known as: Voltaren Ophthalmic
Diclofenac ophthalmic Pregnancy Warnings
Diclofenac ophthalmic has been assigned to pregnancy category C by the FDA. Animal data have revealed evidence of dystocia, prolonged gestation, reduced fetal weights, growth, and survival associated with maternally toxic levels of orally administered diclofenac. Ocularly applied diclofenac undergoes minimal systemic absorption. There are no controlled data in human pregnancy. Diclofenac ophthalmic is only recommended for use during pregnancy when benefit outweighs risk. The manufacturer recommends that the use of diclofenac ophthalmic be avoided during late pregnancy because of the known effects of prostaglandin-inhibiting drugs on the fetal cardiovascular system (premature closure of the ductus arteriosus).
Diclofenac ophthalmic Breastfeeding Warnings
While the manufacturer recommends avoiding diclofenac during lactation, one review paper recommends diclofenac as a suitable nonsteroidal anti-inflammatory agent for use during lactation. The authors based this recommendation on the short half-life and results of a study which failed to detect diclofenac in human milk (less than 10 ng/mL) following either a single 50 mg oral dose or a daily oral dose of 100 mg for 1 week.
There are no data on the excretion of diclofenac ophthalmic into human milk. Because many drugs are excreted in human milk, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
See Also...
- Diclofenac use while Breastfeeding (in more detail)
- diclofenac drops Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
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