Calcium carbonate Pregnancy and Breastfeeding Warnings
Calcium carbonate is also known as: Alka-Seltzer Fruit Chews (Antacid), Amitone, Calcarb, Calcium Oyster Shell, Caltrate, Equilet, Extra Strength Mylanta Calci Tabs, Maalox Regular Strength, Mylanta Child, Nephro Calci, Os-Cal, Os-Cal 500, Oysco 500, Oyst Cal 500, Oyster Cal, Oyster Cal 500, Oyster Calcium, Oyster Shell, Oyster Shell Calcium 500, Pepto Children's, Rolaids Extra Strength Softchews, Titralac, Tums Extra Strength 750, Tums Regular Strength, Tums Ultra 1000
Calcium carbonate Pregnancy Warnings
Calcium carbonate has not been formally assigned to a pregnancy category by the FDA. Animal reproductive studies and data from controlled human studies are not available. Calcium carbonate is commonly used safely to provide calcium supplementation during human pregnancy. Calcium carbonate should only be used during pregnancy when benefit outweighs risk.
Calcium is transported across the human placenta. The human fetus is entirely dependent on its mother for the supply of nutrients--including calcium--and oxygen and removal of waste products. Fetal accumulation of calcium occurs mainly during the third trimester. By the end of normal human pregnancy the fetus acquires approximately 28 grams of calcium and 16 grams of phosphorus for skeletal development. The recommended daily calcium supplementation for a pregnant woman averages 1,200 mg (compared to 800 mg/day in the nonpregnant adult), with an additional 250 to 300 mg/day recommended during the last trimester. One quart of milk contains approximately 1,200 mg of calcium; women who do not consume milk or milk products may require calcium supplementation. The milk-alkali syndrome associated with calcium carbonate has been reported during human pregnancy. In one case, after resolution of hypercalcemia, a 31-year-old woman delivered a stillborn fetus with short limbs and low-set ears at 37 weeks' gestation. Chromosomal analysis was normal, and autopsy revealed no evidence of tissue calcification. In another case, a 31-year-old woman delivered a normal 2,950 gram male infant.
Calcium carbonate Breastfeeding Warnings
The calcium content of human milk averages 30 mg/dl. The recommended daily allowance (RDA) for calcium in the lactating woman is 1,200 mg (compared to 400 mg/day in the nonlactating adult). One quart of milk contains approximately 1,200 mg of calcium. Women who do not consume milk or milk products may require calcium supplementation.
There are no data on the excretion of calcium carbonate into human milk. Calcium is considered a normal component of human milk.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.