Amphotericin b Pregnancy and Breast Feeding Warnings
Amphotericin b is also known as: Amphocin, Fungizone, Fungizone For Tissue Culture
Overview
If you become pregnant, discuss with your doctor the benefits and risks of using Amphotericin B during pregnancy. It is unknown if Amphotericin B is excreted in breast milk. Do not breast-feed while taking Amphotericin B .
Amphotericin b Pregnancy Warnings
Amphotericin B has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal evidence of fetal harm. There are no controlled data in human pregnancy. Amphotericin B should only be given during pregnancy when benefit outweighs risk.
Amphotericin B crosses the human placenta, with cord blood to maternal serum drug concentration ratios averaging up to 1.0. There were no reports of adverse fetal effects or congenital defects associated with amphotericin B in the Collaborative Perinatal Project. This study was a retrospective analysis of 50,282 mother-child pairs, 9 of whom experienced first trimester exposure to amphotericin B.
Amphotericin b Lactation Warnings
There are no data on the excretion of amphotericin B into human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from amphotericin B, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
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