Amphotericin B use while Breastfeeding
Drugs containing Amphotericin B: Fungizone, Amphocin, Fungizone Cream, Fungizone For Tissue Culture, Fungizone Lotion
Amphotericin B Levels and Effects while Breastfeeding
Summary of Use during Lactation
Although no information exists on the milk excretion of amphotericin B, it is highly protein bound, has a large molecular weight, is virtually unabsorbed orally and has been use directly in the mouths of infants;[1] therefore, most reviewers consider it acceptable to use in nursing mothers.[2][3]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
(Systemic) Fluconazole, (Topical) Clotrimazole, Miconazole, Nystatin
References
1. Hoppe JE. Treatment of oropharyngeal candidiasis and candidal diaper dermatitis in neonates and infants: review and reappraisal . Pediatr Infect Dis J. 1997;16:885-94. PMID: 9306485
2. Mactal-Haaf C, Hoffman M, Kuchta A. Use of anti-infective agents during lactation, Part 3: Antivirals, antifungals, and urinary antiseptics. J Hum Lact. 2001;17:160-6. PMID: 11847833
3. Ilett KF, Kristensen JH. Drug use and breastfeeding. Expert Opin Drug Saf. 2005;4:745-68. PMID: 16011452
Amphotericin B Identification
Substance Name
CAS Registry Number
1397-89-3
Drug Class
- Antifungal Agents
Administrative Information
LactMed Record Number
446
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2013-01-24
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Amphotericin b use during Pregnancy
- Amphotericin b Consumer Information
- Amphotericin B topical Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
