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Adapalene / benzoyl peroxide topical Pregnancy and Breastfeeding Warnings

Adapalene / benzoyl peroxide topical is also known as: Epiduo

Adapalene / benzoyl peroxide topical Pregnancy Warnings

Adapalene and benzoyl peroxide topical has been assigned to pregnancy category C by the FDA. Animal studies have not been conducted with adapalene and benzoyl peroxide topical. Teratogenic effects were observed in studies of rats and rabbits given oral doses of adapalene at greater than or equal to 25 times the maximum recommended human dose (MRHD). There are no controlled data in human pregnancy. Adapalene and benzoyl peroxide topical should only be given during pregnancy when the potential benefits outweigh the potential risks.

Adapalene / benzoyl peroxide topical Breastfeeding Warnings

There are no data on the excretion of adapalene and benzoyl peroxide into human milk following topical administration. The manufacturer recommends that caution be used when administering adapalene and benzoyl peroxide topical to a nursing woman.

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