Facts & Comparisons > Lysine

Lysine

Scientific names: 2,6-diaminohexanoic acid, alpha-epsilon-diaminocaproic acid

Efficacy-safety rating:

ÒÒ...Ethno or other evidence of efficacy.

Safety rating:

●...No safety concerns despite wide use.

What is Lysine?

Lysine is an essential amino acid in human nutrition because the body cannot produce it; therefore, it must be taken in either by diet or by supplementation. Lysine was first isolated from casein (a milk phosphoprotein) by Drechsel in 1889.

Lysine may be found in foods such as yogurt, fish, cheese, brewer's yeast, wheat germ, pork, and other meats. Lysine also may be synthesized in the laboratory.

What is Lysine used for?

Overview

Lysine is an amino acid. Amino acids are fundamental constituents of all proteins. They promote protein production, reduce catabolism, promote wound healing and act as buffers in extra- and intracellular fluids.

Miscellaneous uses

Lysine has been studied clinically for the prophylaxis and treatment of herpes infections and cold sores, with mixed results. Lysine improves calcium assimilation and may be helpful in the treatment of Bell's palsy. Lysine acetylsalicylate has been used to treat rheumatoid arthritis and to detoxify heroin. Definitive clinical studies are needed to understand the medicinal uses of lysine.

What is the dosage of Lysine?

Lysine has been given in pure form to athletes and the elderly at daily doses from 1.5 to 3 g daily.

Is Lysine safe?

Contraindications

Lysine supplementation is contraindicated in patients with kidney or liver disease.

Pregnancy/nursing

Information regarding safety and efficacy in pregnancy and lactation is lacking.

Interactions

None well documented.

Side Effects

Dosages up to 4,000 mg/day have been proven to be safe and free of side effects.

Toxicities

There are no reports of human toxicities.

References

Copyright © 2006 Wolters Kluwer Health

Link to Page

Print Page

Email Page

Add to List