Ibrexafungerp

Generic name: ibrexafungerp [ eye-BREX-a-FUNJ-erp ]
Brand name: Brexafemme
Dosage form: oral tablet (150 mg)
Drug class: Miscellaneous antifungals

Medically reviewed by Drugs.com on Jan 11, 2023. Written by Cerner Multum.

What is ibrexafungerp?

Ibrexafungerp is used to treat and reduce the number of repeating vaginal yeast infections in women and in girls who have begun having periods.

Ibrexafungerp may also be used for purposes not listed in this medication guide.

Ibrexafungerp side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects of ibrexafungerp may include:

• headache;

• loose stools, nausea, stomach pain, vomiting; or

• dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Do not use if you are pregnant. Use effective birth control.

Before taking this medicine

You should not use ibrexafungerp if you are allergic to it.

May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using ibrexafungerp and for at least 4 days after your last dose. Tell your doctor if you become pregnant.

You may need to have a negative pregnancy test before starting this treatment. If you are pregnant, you may be enrolled in a pregnancy safety study to track the effects of ibrexafungerp on the baby.

Ask a doctor if it is safe to breastfeed while using ibrexafungerp.

Related/similar drugs

fluconazole, nystatin topical, clotrimazole topical, Diflucan, itraconazole, miconazole topical

How should I take ibrexafungerp?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take ibrexafungerp with or without food.

Ibrexafungerp is usually taken twice per day.

Use this medicine at evenly spaced intervals, about every 12 hours.

Store at room temperature away from moisture and heat.

Ibrexafungerp dosing information

Usual Adult Dose for Vaginal Candidiasis:

For treatment: 300 mg orally twice a day for 1 day (2 doses)
To prevent recurrences: 300 mg orally twice a day for 1 day (2 doses), taken once a month for 6 months

Comments:
-Doses should be administered about 12 hours apart (e.g., in the morning and in the evening).
-The total daily dosage is 600 mg.

Uses:
-For the treatment of adult females with vulvovaginal candidiasis (VVC)
-For reduction in the incidence of recurrent vulvovaginal candidiasis (RVVC) in adult females

Usual Pediatric Dose for Vaginal Candidiasis:

Postmenarchal females:
-For treatment: 300 mg orally twice a day for 1 day (2 doses)
-To prevent recurrences: 300 mg orally twice a day for 1 day (2 doses), taken once a month for 6 months

Comments:
-Doses should be administered about 12 hours apart (e.g., in the morning and in the evening).
-The total daily dosage is 600 mg.

Uses:
-For the treatment of postmenarchal pediatric females with VVC
-For reduction in the incidence of RVVC in postmenarchal pediatric females

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking ibrexafungerp?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect ibrexafungerp?

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Other drugs may affect ibrexafungerp, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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