Questions about Rheumatoid Arthritis? Get answers from our expert.

calcium gluconate

Pronunciation

Generic Name: calcium gluconate (KAL see um GLUE koe nate)
Brand Name:

What is calcium gluconate?

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of your body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body.

Calcium gluconate is used to prevent and to treat calcium deficiencies.

Calcium gluconate may also be used for purposes not listed in this medication guide.

What is the most important information I should know about calcium gluconate?

Do not take calcium gluconate or antacids that contain calcium without first asking your doctor if you also take other medicines. Calcium can make it harder for your body to absorb certain medicines.

Slideshow: Flashback: FDA Drug Approvals 2013

Calcium gluconate works best if you take it with food.

What should I discuss with my healthcare provider before taking calcium gluconate?

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

  • a history of kidney stones; or

  • a parathyroid gland disorder.

Talk to your doctor before taking calcium gluconate if you are pregnant. Your dose needs may be different during pregnancy.

Talk to your doctor before taking calcium gluconate if you are breast-feeding a baby. Your dose needs may be different while you are nursing.

How should I take calcium gluconate?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Calcium gluconate works best if you take it with food.

Take calcium gluconate with a full glass of water.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, decreased appetite, constipation, confusion, and loss of consciousness.

What should I avoid while taking calcium gluconate?

Follow your healthcare provider's instructions about any restrictions on food, beverages, or activity.

Calcium gluconate side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

  • nausea or vomiting;

  • decreased appetite;

  • constipation;

  • dry mouth or increased thirst; or

  • increased urination.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Calcium gluconate dosing information

Usual Adult Dose for Hypocalcemia:

Intravenous:

500 to 2000 mg (5 to 20 mL) IV one time at a rate not to exceed 0.5 to 2 mL/min. The dose may be increased as needed. The usual daily dosage ranges from 1000 to 15,000 mg (10 to 150 mL) in divided doses or as a continuous infusion. Doses may be repeated every 1 to 3 days as needed and tolerated to normalize the serum calcium level.

Oral:

500 to 2000 mg orally 2 to 4 times a day.

Usual Adult Dose for Hypermagnesemia:

1000 to 2000 mg (10 to 20 mL) IV one time at a rate not to exceed 0.5 to 2 mL/min. This dose may be repeated as necessary in severe cases of hypermagnesemia (where discontinuation of exogenous magnesium is inadequate) to temporarily reverse many of the toxic effects of magnesium in the central nervous system.

Usual Adult Dose for Hyperkalemia:

500 to 3000 mg (5 to 30 mL) IV one time at a rate not to exceed 0.5 to 2 mL/min. This dose may be repeated as necessary in cases of extreme hyperkalemia cardiotoxicity when P waves are absent, the QRS complexes are widened, and when continuous ECG monitoring is available. The use of calcium does not reduce the serum potassium level, but counteracts the effects of hyperkalemia on cardiac excitability.

Usual Adult Dose for Exchange Transfusion:

300 mg (3 mL) IV one time with each 100 mL of citrated blood at a rate not to exceed 0.5 to 2 mL/min.

Usual Adult Dose for Osteoporosis:

1000 to 1500 mg/day orally in divided doses.

Usual Pediatric Dose for Hypocalcemia:

Neonatal:
Recommended daily allowance (RDA): (Dosage is in terms of elemental calcium):
Oral: 400 mg/day
Daily maintenance calcium:
IV: 3 to 4 mEq/kg/day
Cardiac arrest in the presence of hyperkalemia or hypocalcemia, magnesium toxicity, or calcium antagonist toxicity: Dosage expressed in mg of calcium gluconate: IV or intraosseous IO:
60 to 100 mg/kg/dose; may repeat in 10 minutes if necessary. If effective, consider IV infusion.
Hypocalcemia (dose depends on clinical condition and serum calcium level):
IV: (Dose expressed in mg of calcium gluconate):
200 to 800 mg/kg/day as a continuous infusion or in 4 divided doses
Oral: (Dosage expressed in mg of elemental calcium):
50 to 150 mg/kg/day in 4 to 6 divided doses
Do not exceed 1 g/day
Dose expressed in mg of calcium gluconate:
500 to 1500 mg/kg/day in 4 to 6 divided doses
Hypocalcemia secondary to citrated blood infusion:
IV:
Give 0.45 mEq elemental calcium for each 100 mL citrated blood infused
Tetany: (Dose expressed in mg of calcium gluconate):
IV: 100 to 200 mg/kg/dose over 5 to 10 minutes; may repeat after 6 hours or follow with an infusion with a maximum dose of 500 mg/kg/day

Dosing: Usual
Adequate intake (AI): (Dosage is in terms of elemental calcium):
Oral:
1 to 6 months: 210 mg/day
7 to 12 months: 270 mg/day
1 to 3 years: 500 mg/day
4 to 8 years: 800 mg/day
9 to 18 years: 1300 mg/day

Recommended daily allowance (RDA): (Dosage is in terms of elemental calcium):
Oral:
1 to 6 months: 400 mg/day
6 to 12 months: 600 mg/day
1 to 10 years: 800 mg/day
11 to 24 years: 1200 mg/day

Hypocalcemia (dose depends on clinical condition and serum calcium level):
Oral: (Dose expressed in mg of elemental calcium):
Children: 45 to 65 mg/kg/day in 4 divided doses

Dose expressed in mg of calcium gluconate:
Infants and Children: 500 to 725 mg/kg/day in 3 to 4 divided doses

Hypocalcemia (dose depends on clinical condition and serum calcium level):
IV: (Dose expressed in mg of calcium gluconate):
Infants and Children: 200 to 500 mg/kg/day as a continuous infusion or in 4 divided doses

Cardiac arrest in the presence of hyperkalemia or hypocalcemia, magnesium toxicity, or calcium antagonist toxicity:
IV, IO: (Dosage expressed in mg of calcium gluconate):
Infants and Children: 60 to 100 mg/kg/dose (maximum: 3 g/dose); may repeat in 10 minutes if necessary; if effective, consider IV infusion.

Hypocalcemia secondary to citrated blood infusion:
IV: Give 0.45 mEq elemental calcium for each 100 mL citrated blood infused

Tetany:
IV: (Dose expressed in mg of calcium gluconate):
Infants and Children: 100 to 200 mg/kg/dose; over 5 to 10 minutes; may repeat after 6 hours or follow with an infusion with a maximum dose of 500 mg/kg/day.

Daily maintenance calcium:
IV:
Infants and Children 25 kg and less: 1 to 2 mEq/kg/day
Children 25 to 45 kg: 0.5 to 1.5 mEq/kg/day
Children greater than 45 kg: 0.2 to 0.3 mEq/kg/day or 10 to 20 mEq/day

What other drugs will affect calcium gluconate?

Calcium gluconate can make it harder for your body to absorb other medications you take by mouth. Tell your doctor if you are taking:

  • digoxin (Lanoxin, Lanoxicaps);

  • antacids or other calcium supplements;

  • calcitriol (Rocaltrol) or vitamin D supplements; or

  • doxycycline (Doryx, Oracea, Periostat, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap).

This list is not complete and other drugs may interact with calcium gluconate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about calcium gluconate.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 4.01. Revision Date: 2012-07-05, 9:58:20 AM.

Hide
(web3)