Blenoxane

Generic Name: bleomycin (BLEE oh MYE sin)
Brand Name: Blenoxane

What is Blenoxane (bleomycin)?

Bleomycin is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Bleomycin is used to treat squamous cell carcinoma, a skin cancer that can affect the mouth, throat, nose and sinuses, penis, vagina, cervix, and other. Bleomycin is also used to treat Hodgkin's disease and non-Hodgkin's lymphoma, testicular cancer, and malignant pleural effusion (a build-up of fluid in the outer tissues of the lungs, caused by certain types of cancer).

Bleomycin treats only the symptoms of prostate cancer but does not treat the cancer itself.

Bleomycin may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Blenoxane (bleomycin)?

Bleomycin is used to treat certain cancers, Hodgkin's disease, non-Hodgkin's lymphoma, or malignant pleural effusion.

To be sure this medication is not causing harmful effects on your lungs, you may need to have chest X-rays or other lung function tests on a regular basis. Do not miss any follow-up visits to your doctor.

Slideshow: HealthQuiz: Basics About Stroke Signs and Symptoms

Call your doctor at once if you have fever, chills, mouth sores, sudden chest pain, shortness of breath, weakness, or severe skin rash.

If you need surgery, tell the surgeon ahead of time that you are being treated with bleomycin.

What should I discuss with my healthcare provider before receiving Blenoxane (bleomycin)?

You should not receive bleomycin if you have ever had an allergic reaction to it.

To make sure you can safely receive bleomycin, tell your doctor if you have any of these other conditions:

  • lung disease or a breathing disorder;

  • kidney disease; or

  • liver disease.

FDA pregnancy category D. Do not use bleomycin if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether bleomycin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is bleomycin given?

Bleomycin is given as an injection through a needle placed into a vein or muscle, or as a shot given under the skin. When treating pleural effusion, bleomycin is given through a chest tube. You will receive this injection in a clinic or hospital setting.

Bleomycin is usually given once or twice per week, depending on the condition being treated. Follow your doctor's instructions.

To be sure this medication is not causing harmful effects on your lungs, you may need to have chest X-rays or other lung function tests on a regular basis.

If you need surgery, tell the surgeon ahead of time that you are being treated with bleomycin.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your bleomycin injection.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving Blenoxane (bleomycin)?

This medicine can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Patients and caregivers should wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Body fluids should not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.

Blenoxane (bleomycin) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fever or chills;

  • sudden chest pain or discomfort, wheezing, dry cough or hack;

  • shortness of breath;

  • confusion, feeling weak or tired, loss of appetite, rapid weight loss;

  • a light-headed feeling, feeling like you might pass out;

  • white patches or sores inside your mouth or on your lips;

  • severe redness, itching, rash, blistering, or tenderness of your skin; or

  • unusual hardening or thickening of your skin.

Common side effects may include:

  • dark streaks or discoloring on your skin;

  • fingernail or toenail changes;

  • temporary hair loss;

  • mild itching;

  • vomiting;

  • pain near your tumor; or

  • redness, warmth, itching, or swelling around the IV needle.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Blenoxane (bleomycin)?

Other drugs may interact with bleomycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about bleomycin.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 6.03. Revision Date: 2013-07-01, 12:23:33 PM.

Hide
(web3)