Does Valerian Root interact with any drugs?

There are over 240 possible drug interactions with valerian, so a drug interaction review by your healthcare provider is important when using this herb. Use caution if combining Valerian with other substances or medicines that cause drowsiness.

Valerian has been used to treat insomnia and anxiety, and people often use it for this effect. It is also promoted for depression, premenstrual syndrome (PMS), menopause symptoms, and headaches.

Most clinical research supports valerian's use to relieve insomnia and improve sleep quality. Germany's Commission E, the authorities that evaluate the use of herbal products in Germany, has approved valerian as an effective mild sedative and it is used for insomnia in that country.

Speak with your doctor before combining valerian with or other medicines that also cause drowsiness or sedation, including:

• muscle relaxants
• sleep or anxiety medicines
• pain killers
• certain antidepressants
• alcohol
• anticonvulsants
• other herbs with a sedating effect, such as chamomile, lemon balm, and catnip.

Avoid activities requiring mental alertness such as driving, operating hazardous machinery, or other dangerous activities until you know how the medications affect you.

Valerian may also slow down how quickly certain drugs are broken down (metabolized) by the liver and may interaction with other medicines that are metabolized this way, as well. This can results in increased side effects or lowered effectiveness of the medicines.

Always tell your doctor and pharmacist about all of the medications you take, including prescription, over-the-counter (OTC), vitamins and herbal or other dietary supplements.

Learn More: View valerian drug interactions (in more detail)

This is not all the information you need to know about Valerian for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.

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