Drug Interaction Report
6 potential interactions and/or warnings found for the following 2 drugs:
- tirzepatide
- Tri-Sprintec (ethinyl estradiol / norgestimate)
Interactions between your drugs
ethinyl estradiol tirzepatide
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate), tirzepatide
Tirzepatide may affect the blood levels and effects of oral contraceptives, which contain hormones such as ethinyl estradiol. This may increase the risk of breakthrough bleeding and unintended pregnancy. Alternative, non-oral methods of birth control should be used, or add another method of birth control (such as condoms) to the oral contraceptive for 4 weeks after starting tirzepatide and for 4 weeks each time after the dose of tirzepatide is increased to avoid unintended pregnancy. Talk to your gynecologist or other healthcare professional if you have any questions or concerns, and for help in selecting an effective method of birth control that is best for you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
norgestimate tirzepatide
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate), tirzepatide
Tirzepatide may affect the blood levels and effects of oral contraceptives, which contain hormones such as norgestimate. This may increase the risk of breakthrough bleeding and unintended pregnancy. Alternative, non-oral methods of birth control should be used, or add another method of birth control (such as condoms) to the oral contraceptive for 4 weeks after starting tirzepatide and for 4 weeks each time after the dose of tirzepatide is increased to avoid unintended pregnancy. Talk to your gynecologist or other healthcare professional if you have any questions or concerns, and for help in selecting an effective method of birth control that is best for you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
norgestimate food
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate)
Grapefruit juice may increase the blood levels of certain medications such as norgestimate. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norgestimate. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
tirzepatide food
Applies to: tirzepatide
Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. Talk to a healthcare provider if you have any questions or concerns, and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ethinyl estradiol food
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate)
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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