D&C Red No. 27 Aluminum Lake
Excipient (pharmacologically inactive substance)
What is D&C Red No. 27 Aluminum Lake?
D&C Red No. 27 Aluminum Lake is a drug and cosmetic synthetic dye. The FDA lists it as a safe additive for drugs and cosmetics as per FDA standards. In cosmetics, it can be used externally and in general cosmetics, including lipsticks and in cosmetics close to the eye.[1]
According to the FDA, lakes are formed by reacting straight dyes (such as D&C Red No. 27) with precipitants and salts. Aluminum is often a component. Lakes may be used as color additives for tablet coatings due to their stability, and may also be used for cosmetics such as eye shadows or lipsticks.[2] Its use in coloring pharmaceuticals and cosmetics may only be of quantities allowable by the FDA.
[1] U.S. Food and Drug Administration (FDA). Cosmetics. Color Additives Permitted for Use. Accessed 8/20/2012. http://www.fda.gov/Cosmetics/GuidanceComplianceRegulatoryInformation/VoluntaryCosmeticsRegistrationProgramVCRP/OnlineRegistration/ucm109084.htm
[2] U.S. Food and Drug Administration. Color Additives and Cosmetics. Updated 4/29/2007. Accessed 8/20/2012. http://www.fda.gov/ForIndustry/ColorAdditives/ColorAdditivesinSpecificProducts/InCosmetics/ucm110032.htm
Top Medications Containing D&C Red No. 27 Aluminum Lake
- Amitriptyline Hydrochloride 10 mg (United Research Laboratories/Mutual Pharmaceutical Company)
- Doxazosin Mesylate 4 mg (Ethex Corporation)
- Glimepiride 4 mg (Mylan Pharmaceuticals Inc.)
- Lortab 10/500 500 mg / 10 mg (UCB Pharma, Inc.)
- Panlor SS 712.8 mg / 60 mg / 32 mg (Pamlab LLC)
- Pentoxil 400 mg (Upsher-Smith Laboratories, Inc)
- Phrenilin acetaminophen 325 mg / butalbital 50 mg (Valeant Pharmaceuticals International)
