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Metreleptin and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with metreleptin.

Major

Metreleptin Obesity

Major Potential Hazard, High plausibility

metreleptin - obesity

The use of metreleptin is contraindicated in patients with general obesity not associated with congenital leptin deficiency. Metreleptin has not been shown to be effective in treating general obesity. Moreover, development of anti-metreleptin antibodies with neutralizing activity has been reported in obese patients treated with metreleptin, the clinical consequences of which have not been well characterized but could include inhibition of endogenous leptin action and loss of metreleptin efficacy. Worsening metabolic control and/or severe infection have been reported.

References

  1. (2014) "Product Information. Myalept (metreleptin)." Bristol-Myers Squibb

Metreleptin drug interactions

There are 181 drug interactions with metreleptin.

Metreleptin disease interactions

There are 4 disease interactions with metreleptin which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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