Istradefylline and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with istradefylline.
Istradefylline Food
Moderate Food Interaction
ADJUST DOSE: Smoking tobacco may decrease the steady-state systemic exposure of istradefylline by 38% to 54%.
MANAGEMENT: The possibility of reduced therapeutic effects of istradefylline should be considered in smokers. The manufacturer recommends an istradefylline dosage of 40 mg once daily in patients who smoke 20 or more cigarettes (or the equivalent amount of another tobacco product) per day.
References
- (2019) "Product Information. Nourianz (istradefylline)." Kyowa Kirin, Inc
Istradefylline drug interactions
There are 173 drug interactions with istradefylline.
Istradefylline disease interactions
There are 4 disease interactions with istradefylline which include:
More about istradefylline
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- During pregnancy
- Drug class: miscellaneous antiparkinson agents
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.