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Cilastatin/imipenem and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with cilastatin / imipenem.

Moderate

High Blood Pressure (Hypertension)

Moderate Potential Hazard, High plausibility

imipenem - sodium

The intramuscular and intravenous formulations of imipenem-cilastatin contain 32 mg (1.4 mEq) and 37.5 mg (1.6 mEq) of sodium, respectively, per each 500 mg of imipenem activity. The sodium content should be considered when these products are used in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention.

References

  1. "Product Information. Primaxin (imipenem)." Merck & Co., Inc PROD (2002):

Cilastatin/imipenem drug interactions

There are 37 drug interactions with cilastatin / imipenem.

Cilastatin/imipenem disease interactions

There are 5 disease interactions with cilastatin / imipenem which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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