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Drug Interactions between smallpox and mpox vaccine and Tembexa

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

brincidofovir smallpox and monkeypox vaccine

Applies to: Tembexa (brincidofovir) and smallpox and mpox vaccine

Brincidofovir may interfere with the immune response produced by smallpox and monkeypox vaccine. However, use of brincidofovir with vaccines such as smallpox and monkeypox vaccine has not been studied in humans. Your doctor should be informed of recent medication and vaccination history so that appropriate measures and/or precautions can be taken. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any other medications without first talking to your doctor.

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Drug and food interactions

Moderate

brincidofovir food

Applies to: Tembexa (brincidofovir)

Food may decrease the blood levels of brincidofovir. It is recommended that you take brincidofovir on an empty stomach, meaning no food should be eaten for at least two hours before or after taking brincidofovir. If necessary, you may take the oral tablets (but not the suspension formulation) with a low-fat meal. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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