Drug interactions between Procardia and quinidine
Results for the following 2 drugs: |
|
|---|---|
| Procardia (nifedipine) | |
| quinidine | |
Interactions between your selected drugs
quinidine ⇔ nifedipine
Applies to: quinidine and Procardia (nifedipine)
MONITOR: Some dihydropyridine calcium channel blockers may increase or decrease serum quinidine concentrations by an unknown mechanism. Data have been conflicting. No changes in quinidine concentrations have also been reported. Increased quinidine levels have been associated with QTc prolongation. In addition, quinidine may increase calcium channel blocker levels.
MANAGEMENT: It is recommended that the effectiveness of quinidine and the calcium channel blocker be monitored and that serum quinidine levels be checked when clinically appropriate. Patients should be advised to promptly report any early symptoms of quinidine toxicity (e.g., nausea, vomiting, diarrhea, tinnitus, hearing loss, visual disturbances, dizziness, headache, and confusion) or excessive calcium channel blockade (e.g., hypotension and lower extremity edema).
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