Drug interactions between omeprazole and Theo-Dur
| Results for the following 2 drugs: |
|---|
| omeprazole |
| Theo-Dur (theophylline) |
Interactions between your selected drugs
theophylline ↔ omeprazole
Applies to:Theo-Dur (theophylline) and omeprazole
MONITOR: Proton pump inhibitors may increase the rate of theophylline absorption from sustained-release formulations. Chronic use of proton pump inhibitors produce sustained hypochlorhydria, which may enhance peristalsis in the small intestine and antiperistalsis in the proximal colon where theophylline is absorbed.
MANAGEMENT: In patients treated with proton pump inhibitors, the possibility of an enhanced pharmacologic response to sustained-release theophylline should be considered. Patients should be closely monitored for development of toxicity, particularly those with theophylline levels in the upper range of normal. Patients should be advised to report any signs of theophylline toxicity including nausea, vomiting, diarrhea, headache, restlessness, insomnia, or irregular heartbeat to their physicians.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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