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Drug Interactions between Northyx and Permitil

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

fluPHENAZine methIMAzole

Applies to: Permitil (fluphenazine) and Northyx (methimazole)

Talk to your doctor before using fluPHENAZine together with methIMAzole. Combining these medications may increase the risk of agranulocytosis, a rare but serious and potentially fatal disorder that affects white blood cells. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you develop signs and symptoms of infection such as fever, chills, body aches, sore throat, coughing, breathing difficulties, mouth ulcers, or flu-like symptoms. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

fluPHENAZine food

Applies to: Permitil (fluphenazine)

Ask your doctor before using fluPHENAZine together with ethanol. This can cause uncontrollable movements, agitation, seizures, severe dizziness or fainting, coma, very deep sleep, irregular heartbeats, and high or low body temperature. Use caution when driving, operating machinery, or performing other hazardous activities, these medicaions may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.