Drug Interactions between norgestrel and Targretin
This report displays the potential drug interactions for the following 2 drugs:
- norgestrel
- Targretin (bexarotene)
Interactions between your drugs
norgestrel bexarotene
Applies to: norgestrel and Targretin (bexarotene)
Bexarotene may decrease the effectiveness of norgestrel. If you are using low-dose contraceptives, there is an increased risk of unintended pregnancy during combined therapy with bexarotene. Bexarotene is likely associated with major birth defects, it is particularly important that you do not become pregnant during treatment. Therefore, hormonal contraceptives should not be used as the sole method of birth control in women of childbearing potential treated with bexarotene. Alternative or additional methods of birth control should be used while taking bexarotene. If you take hormone replacement for menopause, notify your doctor if you have decreased efficacy of your hormones. You may notice symptoms of increased hot flashes, vaginal dryness or menstrual abnormalities. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.
Drug and food interactions
norgestrel food
Applies to: norgestrel
Grapefruit juice may increase the blood levels of certain medications such as norgestrel. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norgestrel. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
bexarotene food
Applies to: Targretin (bexarotene)
Food helps with the absorption of bexarotene from the gastrointestinal tract into the blood stream. You should take each dose the same time everyday with a meal. Avoid consuming large amounts of grapefruit or grapefruit juice during treatment, since doing so may increase the blood levels of bexarotene. Talk to your doctor or pharmacist if you have any questions or concerns about your medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
norgestrel food
Applies to: norgestrel
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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