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Drug Interactions between nilotinib and TheraCys

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

BCG nilotinib

Applies to: TheraCys (bcg) and nilotinib

If you are currently being treated or have recently been treated with nilotinib, you should let your doctor know before receiving BCG. Depending on the dose and length of time you have been on nilotinib, you may be at risk for developing an infection from BCG or have a reduced response to BCG. In some situations, your doctor may want to delay treatment with BCG to give your body time to recover from the effects of nilotinib therapy. Additionally, since the bacteria in BCG may persist in the urinary tract for months after treatment, you may still be at increased risk for infection even if you receive nilotinib after you have stopped treatment with BCG for some time. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

nilotinib food

Applies to: nilotinib

Do not consume grapefruit or grapefruit juice during treatment with nilotinib unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of nilotinib to dangerous levels, increasing the risk of an irregular heart rhythm that may be serious. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with nilotinib. Food may also increase the blood levels of nilotinib. Therefore, you should take nilotinib on an empty stomach, meaning no food should be eaten for at least two hours before or one hour after taking nilotinib. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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