Drug interactions between Nicotrol Inhaler and ranitidine
Results for the following 2 drugs: |
|
|---|---|
| Nicotrol Inhaler (nicotine) | |
| ranitidine | |
Interactions between your selected drugs
ranitidine ⇔ nicotine
Applies to: ranitidine and Nicotrol Inhaler (nicotine)
H2 antagonists may reduce the clearance of nicotine. Cimetidine, 600 mg given twice a day for two days, reduced clearance of an intravenous nicotine dose by 30%. Ranitidine, 300 mg given twice a day for two days, reduced clearance by 10%. The clinical significance of this interaction is not known. Patients should be monitored for increased nicotine effects when using the patches or gum for smoking cessation and dosage adjustments should be made as appropriate.
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