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Drug Interactions between mefloquine and Potiga

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

mefloquine ezogabine

Applies to: mefloquine and Potiga (ezogabine)

Mefloquine may increase the risk of seizures and reduce the effectiveness of ezogabine in the treatment of epilepsy. If you are receiving ezogabine for epilepsy, you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience a loss of seizure control or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

mefloquine food

Applies to: mefloquine

Food can enhance the levels of mefloquine in your body. Take mefloquine immediately after a meal. This will make it easier for your body to absorb the medication. Take each dose with a full glass, at least 8 ounces (240 mL) of water. For children or those who have difficulty swallowing, mefloquine can be crushed and mixed with water or sugar water. Talk to your healthcare provider if swallowing the tablets is difficult.

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Moderate

ezogabine food

Applies to: Potiga (ezogabine)

Alcohol can increase the blood levels of ezogabine and worsen side effects such as drowsiness, dizziness, nausea, constipation, difficulty urinating, blurred vision, memory impairment, and tremor. You should avoid or limit the use of alcohol while being treated with ezogabine. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Ezogabine may be taken with or without food. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.