Drug interactions between immune globulin intravenous and yellow fever vaccine
Results for the following 2 drugs: |
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|---|---|
| immune globulin intravenous | |
| yellow fever vaccine | |
Interactions between your selected drugs
immune globulin intravenous ↔ yellow fever vaccine
Applies to:immune globulin intravenous and yellow fever vaccine
ADJUST DOSING INTERVAL: The passive transfer of antibodies present in immune globulin preparations may interfere with the immune response to live vaccines.
MANAGEMENT: Varicella virus vaccine should not be given for at least 5 months, and other live vaccines should not be given for at least 3 months, after administration of immune globulin. If such vaccinations are given shortly before or after immune globulin therapy, a revaccination may be necessary. Some experts have recommended that administration of measles virus vaccine be deferred for at least 8 months following human intravenous immune globulin therapy for immunodeficiency disease; 8 to 10 months following treatment for immune thrombocytopenic purpura (ITP); and at least 11 months following treatment for Kawasaki syndrome. In the event that immune globulin and measles virus vaccine must be administered concurrently, it is advisable to separate the injection sites by as much as possible and to administer an additional dose of vaccine at the appropriate specified interval. An additional dose of live measles, mumps, or rubella vaccine is usually not needed if the vaccine was administered at least two weeks prior to immune globulin administration. Hepatitis B immune globulin has been reported to not interfere with measles vaccination, although data are limited.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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